erythematosus and reveals genetic linkages at 1q22 and 11p13 Thrombocytopenia identifies a severe familial phenotype of systemic lupus
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منابع مشابه
Thrombocytopenia identifies a severe familial phenotype of systemic lupus erythematosus and reveals genetic linkages at 1q22 and 11p13.
Systemic lupus erythematosus (SLE) is a complicated autoimmune disease with a definite genetic predisposition. Thrombocytopenia predicts severe disease and death in SLE, making the identification of the related genetic risk factors especially important. We selected the 38 pedigrees that had an SLE patient with thrombocytopenia (platelets, < 10 x 10(9)/L [< 100,000/microL]) from a collection of ...
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Hematologic abnormali"es are generally present among systemic lupus erythematosus pa"ents. Idiopathic thrombocytopenic purpura can be the first manifesta"on of SLE, followed by other symptoms and signs of disease appearing several years later. Although bleeding due to immune thrombocytopenic purpura is usually mild and occurs in mucocutaneous surfaces, but it may be severe and represent in u...
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